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Chelsea matches where Mark Hughes was opposition manager/coach
| Date | Venue | Opponent | Score | Comp |
| 23/10/2004 | Stamford Bridge | Blackburn Rovers | 4-0 | Premier League |
| 02/02/2005 | Ewood Park | Blackburn Rovers | 1-0 | Premier League |
| 29/10/2005 | Stamford Bridge | Blackburn Rovers | 4-2 | Premier League |
| 02/05/2006 | Ewood Park | Blackburn Rovers | 0-1 | Premier League |
| 27/08/2006 | Ewood Park | Blackburn Rovers | 2-0 | Premier League |
| 25/10/2006 | Ewood Park | Blackburn Rovers | 2-0 | Carling Cup |
| 31/01/2007 | Stamford Bridge | Blackburn Rovers | 3-0 | Premier League |
| 15/04/2007 | Old Trafford | Blackburn Rovers | 2-1 | F.A. Cup |
| 15/09/2007 | Stamford Bridge | Blackburn Rovers | 0-0 | Premier League |
| 23/12/2007 | Ewood Park | Blackburn Rovers | 1-0 | Premier League |
| 13/09/2008 | City Of Manchester Stadium | Manchester City | 3-1 | Premier League |
| 15/03/2009 | Stamford Bridge | Manchester City | 1-0 | Premier League |
| 05/12/2009 | City Of Manchester Stadium | Manchester City | 1-2 | Premier League |
| 10/11/2010 | Stamford Bridge | Fulham | 1-0 | Premier League |
| 14/02/2011 | Craven Cottage | Fulham | 0-0 | Premier League |
| 28/01/2012 | Loftus Road | Queens Park Rangers | 1-0 | F.A. Cup |
| 29/04/2012 | Stamford Bridge | Queens Park Rangers | 6-1 | Premier League |
| 15/09/2012 | Loftus Road | Queens Park Rangers | 0-0 | Premier League |
| 07/12/2013 | Britannia Stadium | Stoke City | 2-3 | Premier League |
| 26/01/2014 | Stamford Bridge | Stoke City | 1-0 | F.A. Cup |
| 05/04/2014 | Stamford Bridge | Stoke City | 3-0 | Premier League |
| 22/12/2014 | Britannia Stadium | Stoke City | 2-0 | Premier League |
| 04/04/2015 | Stamford Bridge | Stoke City | 2-1 | Premier League |
| 27/10/2015 | Britannia Stadium | Stoke City | 1-1 | Capital One Cup |
| 07/11/2015 | Britannia Stadium | Stoke City | 0-1 | Premier League |
| 05/03/2016 | Stamford Bridge | Stoke City | 1-1 | Premier League |
| 31/12/2016 | Stamford Bridge | Stoke City | 4-2 | Premier League |
| 18/03/2017 | bet365 Stadium | Stoke City | 2-1 | Premier League |
| 23/09/2017 | bet365 Stadium | Stoke City | 4-0 | Premier League |
| 30/12/2017 | Stamford Bridge | Stoke City | 5-0 | Premier League |
| 14/04/2018 | St Mary's Stadium | Southampton | 3-2 | Premier League |
| 22/04/2018 | Wembley | Southampton | 2-0 | F.A. Cup |
| 07/10/2018 | St Mary's Stadium | Southampton | 3-0 | Premier League |